PUBLICATIONS

Analysis of simplicial complexes to determine when to sample for quantitative DCE MRI of the breast.
DiCarlo JC, Jarrett AM, Kazerouni AS, Virostko J, Sorace A, Slavkova KP, Woodard S, Avery S, Patt D, Goodgame B, Yankeelov TE
Magnetic resonance in medicine. 2022 Nov 2; : . doi: 10.1002/mrm.29511
PMID: 36321574
Proteogenomic Markers of Chemotherapy Resistance and Response in Triple-Negative Breast Cancer.
Anurag M, Jaehnig EJ, Krug K, Lei JT, Bergstrom EJ, Kim BJ, Vashist TD, Huynh AMT, Dou Y, Gou X, Huang C, Shi Z, Wen B, Korchina V, Gibbs RA, Muzny DM, Doddapaneni H, Dobrolecki LE, Rodriguez H, Robles AI, Hiltke T, Lewis MT, Nangia JR, Nemati Shafaee M, Li S, Hagemann IS, Hoog J, Lim B, Osborne CK, Mani DR, Gillette MA, Zhang B, Echeverria GV, Miles G, Rimawi MF, Carr SA, Ademuyiwa FO, Satpathy S, Ellis MJ
Cancer discovery. ; 12: 2586-2605. doi: 10.1158/2159-8290.CD-22-0200
PMID: 36001024
Towards Patient-Specific Optimization of Neoadjuvant Treatment Protocols for Breast Cancer Based on Image-Guided Fluid Dynamics.
Wu C, Hormuth DA, Lorenzo G, Jarrett AM, Pineda F, Howard FM, Karczmar GS, Yankeelov TE
IEEE transactions on bio-medical engineering. 2022 Oct 19; 69: 3334-3344. doi: 10.1109/TBME.2022.3168402
PMID: 35439121
PET Oncological Radiopharmaceuticals: Current Status and Perspectives.
Lin M, Coll RP, Cohen AS, Georgiou DK, Manning HC
Molecules (Basel, Switzerland). 2022 Oct 11; 27: . pii: 6790. doi: 10.3390/molecules27206790
PMID: 36296381
MRI-Based Digital Models Forecast Patient-Specific Treatment Responses to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer.
Wu C, Jarrett AM, Zhou Z, Elshafeey N, Adrada BE, Candelaria RP, Mohamed RMM, Boge M, Huo L, White JB, Tripathy D, Valero V, Litton JK, Yam C, Son JB, Ma J, Rauch GM, Yankeelov TE
Cancer research. ; 82: 3394-3404. doi: 10.1158/0008-5472.CAN-22-1329
PMID: 35914239
Machine Learning-Enabled Multimodal Fusion of Intra-Atrial and Body Surface Signals in Prediction of Atrial Fibrillation Ablation Outcomes.
Tang S, Razeghi O, Kapoor R, Alhusseini MI, Fazal M, Rogers AJ, Rodrigo Bort M, Clopton P, Wang PJ, Rubin DL, Narayan SM, Baykaner T
Circulation. Arrhythmia and electrophysiology. 2022 Jul 22; 15: e010850. doi: 10.1161/CIRCEP.122.010850
PMID: 35867397
Opportunities for improving brain cancer treatment outcomes through imaging-based mathematical modeling of the delivery of radiotherapy and immunotherapy.
Hormuth DA 2nd, Farhat M, Christenson C, Curl B, Chad Quarles C, Chung C, Yankeelov TE
Advanced drug delivery reviews. 2022 May 30; 187: 114367. doi: 10.1016/j.addr.2022.114367
PMID: 35654212
Genomic and epigenomic BRCA alterations predict adaptive resistance and response to platinum-based therapy in patients with triple-negative breast and ovarian carcinomas.
Menghi F, Banda K, Kumar P, Straub R, Dobrolecki L, Rodriguez IV, Yost SE, Chandok H, Radke MR, Somlo G, Yuan Y, Lewis MT, Swisher EM, Liu ET
Science translational medicine. 2022 Jul 6; 14: eabn1926. doi: 10.1126/scitranslmed.abn1926
PMID: 35857626
Quantifying Tumor Heterogeneity via MRI Habitats to Characterize Microenvironmental Alterations in HER2+ Breast Cancer.
Kazerouni AS, Hormuth DA 2nd, Davis T, Bloom MJ, Mounho S, Rahman G, Virostko J, Yankeelov TE, Sorace AG
Cancers. 2022 Apr 6; 14: . pii: 1837. doi: 10.3390/cancers14071837
PMID: 35406609
Quantification of long-term doxorubicin response dynamics in breast cancer cell lines to direct treatment schedules.
Howard GR, Jost TA, Yankeelov TE, Brock A
PLoS computational biology. 2022 Mar 31; 18: e1009104. doi: 10.1371/journal.pcbi.1009104
PMID: 35358172
First-in-Human PET Imaging and Estimated Radiation Dosimetry of l-[5-11C]-Glutamine in Patients with Metastatic Colorectal Cancer.
Cohen AS, Grudzinski J, Smith GT, Peterson TE, Whisenant JG, Hickman TL, Ciombor KK, Cardin D, Eng C, Goff LW, Das S, Coffey RJ, Berlin JD, Manning HC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2021 Apr 30; 63: 36-43. doi: 10.2967/jnumed.120.261594
PMID: 33931465
Bayesian calibration of a stochastic, multiscale agent-based model for predicting in vitro tumor growth.
Lima EABF, Faghihi D, Philley R, Yang J, Virostko J, Phillips CM, Yankeelov TE
PLoS computational biology. 2021 Nov 29; 17: e1008845. doi: 10.1371/journal.pcbi.1008845
PMID: 34843457
Quantitative multiparametric MRI predicts response to neoadjuvant therapy in the community setting.
Virostko J, Sorace AG, Slavkova KP, Kazerouni AS, Jarrett AM, DiCarlo JC, Woodard S, Avery S, Goodgame B, Patt D, Yankeelov TE
Breast cancer research : BCR. 2021 Nov 27; 23: 110. doi: 10.1186/s13058-021-01489-6
PMID: 34838096
Quantitative magnetic resonance imaging and tumor forecasting of breast cancer patients in the community setting.
Jarrett AM, Kazerouni AS, Wu C, Virostko J, Sorace AG, DiCarlo JC, Hormuth DA 2nd, Ekrut DA, Patt D, Goodgame B, Avery S, Yankeelov TE
Nature protocols. 2021 Sep 22; 16: 5309-5338. doi: 10.1038/s41596-021-00617-y
PMID: 34552262
An in silico validation framework for quantitative DCE-MRI techniques based on a dynamic digital phantom.
Wu C, Hormuth DA 2nd, Easley T, Eijkhout V, Pineda F, Karczmar GS, Yankeelov TE
Medical image analysis. 2021 Jul 20; 73: 102186. doi: 10.1016/j.media.2021.102186
PMID: 34329903
A time-resolved experimental-mathematical model for predicting the response of glioma cells to single-dose radiation therapy.
Liu J, Hormuth DA, Davis T, Yang J, McKenna MT, Jarrett AM, Enderling H, Brock A, Yankeelov TE
Integrative biology : quantitative biosciences from nano to macro. ; 13: 167-183. doi: 10.1093/intbio/zyab010
PMID: 34060613
Characterizing Errors in Pharmacokinetic Parameters from Analyzing Quantitative Abbreviated DCE-MRI Data in Breast Cancer.
Slavkova KP, DiCarlo JC, Kazerouni AS, Virostko J, Sorace AG, Patt D, Goodgame B, Yankeelov TE
Tomography (Ann Arbor, Mich.). 2021 Jun 23; 7: 253-267. doi: 10.3390/tomography7030023
PMID: 34201654
Biologically-Based Mathematical Modeling of Tumor Vasculature and Angiogenesis via Time-Resolved Imaging Data.
Hormuth DA 2nd, Phillips CM, Wu C, Lima EABF, Lorenzo G, Jha PK, Jarrett AM, Oden JT, Yankeelov TE
Cancers. 2021 Jun 16; 13: . pii: 3008. doi: 10.3390/cancers13123008
PMID: 34208448
Image-based personalization of computational models for predicting response of high-grade glioma to chemoradiation.
Hormuth DA 2nd, Al Feghali KA, Elliott AM, Yankeelov TE, Chung C
Scientific reports. 2021 Apr 19; 11: 8520. doi: 10.1038/s41598-021-87887-4
PMID: 33875739
Data valuation for medical imaging using Shapley value and application to a large-scale chest X-ray dataset.
Tang S, Ghorbani A, Yamashita R, Rehman S, Dunnmon JA, Zou J, Rubin DL
Scientific reports. 2021 Apr 16; 11: 8366. doi: 10.1038/s41598-021-87762-2
PMID: 33863957
Towards an Image-Informed Mathematical Model of In Vivo Response to Fractionated Radiation Therapy.
Hormuth DA 2nd, Jarrett AM, Davis T, Yankeelov TE
Cancers. 2021 Apr 7; 13: . pii: 1765. doi: 10.3390/cancers13081765
PMID: 33917080
Anatase Titanium Dioxide Imparts Photoluminescent Properties to PA2200 Commercial 3D Printing Material to Generate Complex Optical Imaging Phantoms.
Dann T, Raphel J, Gammon ST, Mastrovich Z, Van Avermaete T, Jeffrey J, Adusumilli S, Leevy WM
Materials (Basel, Switzerland). 2021 Apr 6; 14: . pii: 1813. doi: 10.3390/ma14071813
PMID: 33917612
ARID1A Mutation May Define an Immunologically Active Subgroup in Patients with Microsatellite Stable Colorectal Cancer.
Mehrvarz Sarshekeh A, Alshenaifi J, Roszik J, Manyam GC, Advani SM, Katkhuda R, Verma A, Lam M, Willis J, Shen JP, Morris J, Davis JS, Loree JM, Lee HM, Ajani JA, Maru DM, Overman MJ, Kopetz S
Clinical cancer research : an official journal of the American Association for Cancer Research. 2021 Jan 7; 27: 1663-1670. doi: 10.1158/1078-0432.CCR-20-2404
PMID: 33414133
The rate of breast fibroglandular enhancement during dynamic contrast-enhanced MRI reflects response to neoadjuvant therapy.
Virostko J, Kuketz G, Higgins E, Wu C, Sorace AG, DiCarlo JC, Avery S, Patt D, Goodgame B, Yankeelov TE
European journal of radiology. 2021 Jan 9; 136: 109534. doi: 10.1016/j.ejrad.2021.109534
PMID: 33454460
Math, magnets, and medicine: enabling personalized oncology.
Hormuth DA 2nd, Jarrett AM, Lorenzo G, Lima EABF, Wu C, Chung C, Patt D, Yankeelov TE
Expert review of precision medicine and drug development. 2021 Jan 27; 6: 79-81. doi: 10.1080/23808993.2021.1878023
PMID: 34027102
Evaluating patient-specific neoadjuvant regimens for breast cancer via a mathematical model constrained by quantitative magnetic resonance imaging data.
Jarrett AM, Hormuth DA 2nd, Wu C, Kazerouni AS, Ekrut DA, Virostko J, Sorace AG, DiCarlo JC, Kowalski J, Patt D, Goodgame B, Avery S, Yankeelov TE
Neoplasia (New York, N.Y.). 2020 Nov 14; 22: 820-830. doi: 10.1016/j.neo.2020.10.011
PMID: 33197744
Integrating transcriptomics and bulk time course data into a mathematical framework to describe and predict therapeutic resistance in cancer.
Johnson KE, Howard GR, Morgan D, Brenner EA, Gardner AL, Durrett RE, Mo W, Al'Khafaji A, Sontag ED, Jarrett AM, Yankeelov TE, Brock A
Physical biology. 2020 Nov 20; 18: 016001. doi: 10.1088/1478-3975/abb09c
PMID: 33215611
TSPO-targeted PET and Optical Probes for the Detection and Localization of Premalignant and Malignant Pancreatic Lesions.
Cohen AS, Li J, Hight MR, McKinley E, Fu A, Payne A, Liu Y, Zhang D, Xie Q, Bai M, Ayers GD, Tantawy MN, Smith JA, Revetta F, Washington MK, Shi C, Merchant N, Manning HC
Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Sep 15; 26: 5914-5925. doi: 10.1158/1078-0432.CCR-20-1214
PMID: 32933996
Imaging for Response Assessment in Cancer Clinical Trials.
Sorace AG, Elkassem AA, Galgano SJ, Lapi SE, Larimer BM, Partridge SC, Quarles CC, Reeves K, Napier TS, Song PN, Yankeelov TE, Woodard S, Smith AD
Seminars in nuclear medicine. 2020 Jun 10; 50: 488-504. doi: 10.1053/j.semnuclmed.2020.05.001
PMID: 33059819
Combined blockade of EGFR and glutamine metabolism in preclinical models of colorectal cancer.
Cohen AS, Geng L, Zhao P, Fu A, Schulte ML, Graves-Deal R, Washington MK, Berlin J, Coffey RJ, Manning HC
Translational oncology. 2020 Jul 8; 13: 100828. doi: 10.1016/j.tranon.2020.100828
PMID: 32652471
Co-Clinical Imaging Resource Program (CIRP): Bridging the Translational Divide to Advance Precision Medicine.
Shoghi KI, Badea CT, Blocker SJ, Chenevert TL, Laforest R, Lewis MT, Luker GD, Manning HC, Marcus DS, Mowery YM, Pickup S, Richmond A, Ross BD, Vilgelm AE, Yankeelov TE, Zhou R
Tomography (Ann Arbor, Mich.). ; 6: 273-287. doi: 10.18383/j.tom.2020.00023
PMID: 32879897
Patient-Specific Characterization of Breast Cancer Hemodynamics Using Image-Guided Computational Fluid Dynamics.
Wu C, Hormuth DA, Oliver TA, Pineda F, Lorenzo G, Karczmar GS, Moser RD, Yankeelov TE
IEEE transactions on medical imaging. 2020 Feb 20; 39: 2760-2771. doi: 10.1109/TMI.2020.2975375
PMID: 32086203
N-[18F]-Fluoroacetylcrizotinib: A potentially potent and selective PET tracer for molecular imaging of non-small cell lung cancer.
Buck JR, Saleh S, Claus T, Lovly C, Hight MR, Nickels ML, Noor Tantawy M, Charles Manning H
Bioorganic & medicinal chemistry letters. 2020 Jun 2; 30: 127257. doi: 10.1016/j.bmcl.2020.127257
PMID: 32631505
Multiparametric Analysis of Longitudinal Quantitative MRI data to Identify Distinct Tumor Habitats in Preclinical Models of Breast Cancer.
Syed AK, Whisenant JG, Barnes SL, Sorace AG, Yankeelov TE
Cancers. 2020 Jun 24; 12: . pii: E1682. doi: 10.3390/cancers12061682
PMID: 32599906
The Influence of Chronic Liver Diseases on Hepatic Vasculature: A Liver-on-a-chip Review.
Özkan A, Stolley D, Cressman ENK, McMillin M, DeMorrow S, Yankeelov TE, Rylander MN
Micromachines. 2020 May 9; 11: . pii: E487. doi: 10.3390/mi11050487
PMID: 32397454
Optimal Control Theory for Personalized Therapeutic Regimens in Oncology: Background, History, Challenges, and Opportunities.
Jarrett AM, Faghihi D, Ii DAH, Lima EABF, Virostko J, Biros G, Patt D, Yankeelov TE
Journal of clinical medicine. 2020 May 2; 9: . pii: E1314. doi: 10.3390/jcm9051314
PMID: 32370195
Automated radiosynthesis of 5-[11C]l-glutamine, an important tracer for glutamine utilization.
Rosenberg AJ, Nickels ML, Schulte ML, Manning HC
Nuclear medicine and biology. 2018 Oct 15; 67: 10-14. doi: 10.1016/j.nucmedbio.2018.09.002
PMID: 30359787